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Actress Mayim Bialik shares her ‘nightmare’ experience with a GLP-1

RocksInMyHead

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That is what they're looking for though based on the link I provided earlier...if the large uptake is among young people who aren't diabetic, upper income, and targeting weight loss under <15 lbs....

What better descriptors would one use?
You posted the link you're referring to two days after saying that. You're not going to blame people for not reading your mind, are you? And it's still unnecessarily pejorative.
 
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ThatRobGuy

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You posted the link you're referring to two days after saying that. You're not going to blame people for not reading your mind, are you? And it's still unnecessarily pejorative.
What would be the nice way to say it?

"Some young people want to lose 15 lbs so they look better, but don't want to diet or exercise" isn't exactly flattering either. There are certain things that there's just no "super happy" way of saying.
 
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RileyG

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It's the worst. I remember not feeling well, then I went into the doctor and the nurse saw me in the waiting room and stopped dead in her tracks and said "you are having an allergic reaction to prednisone, go to the ER." She wasn't even my nurse who knew what I was taking. She was just a nurse.

That said, it did cause one of the funniest incidents in my marriage (in hindsight). I was horribly sick with Crohn's, getting sick off of everything I ate and drank, except for Haribo and Skittles. I texted my husband (who was at work) and asked him to bring home Skittles. In my mind, he would go to the wholesale club near him and get one of those huge pillow case-sized bag of Skittles. He actually ended up stopping at the gas station and getting me two king size bags. He comes home, gives them to me, and I looked at them completely flabbergasted. I hold them up and say "what are these?" and he says "they're your Skittles. I got two flavors just in case." He was expecting an "oh thank you!" but instead I held them up and yelled "NO, I WANTED SKITTLES.... WHAT THE HECK DO YOU THINK I'M GOING TO DO WITH THESE?????" then hysterically cried about how he didn't listen to me, now I was stuck with these wrong-sized Skittles that I'd blow through in two handfuls, and just generally ranted and raved like an insane person. He calmly got his keys, went back out, and got me the big bag of Skittles from the wholesale club. He comes back and gives them to me, I tear into them like a feral animal, eyes red and still hiccuping from crying so hard earlier. I'm eating them by the fist full and my husband calmly sits down next to me, puts his hand on my knee, and says "so... you want to talk about what just happened?" I was back to howling through tears while intermittently stuffing my face with Skittles, saying I know I overreacted, I was sorry, I didn't know why I was being so crazy... My poor husband just said "ok... nevermind.... it's ok" and got up and gave me all the space while I sobbed and ate Skittles.

Come to find out that it was a side effect of the Prednisone allergy. We laugh about it now and my husband still yells "AND WHAT DO YOU THINK I'M GOING TO DO WITH THESE?????" or "it's candy... you eat it" whenever he gets me candy.
I’m happy to hear you’re doing better.

Take care
 
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RocksInMyHead

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What would be the nice way to say it?

"Some young people want to lose 15 lbs so they look better, but don't want to diet or exercise" isn't exactly flattering either. There are certain things that there's just no "super happy" way of saying.
Why does it need to be said in the first place? Whether or not you think someone needs a weight loss drug is irrelevant to a discussion of lax prescription patterns. The issue isn't that "undeserving" people are getting access, but rather that some doctors are potentially not properly evaluating patients (or communicating risks) before giving them prescriptions.
 
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ThatRobGuy

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Why does it need to be said in the first place? Whether or not you think someone needs a weight loss drug is irrelevant to a discussion of lax prescription patterns. The issue isn't that "undeserving" people are getting access, but rather that some doctors are potentially not properly evaluating patients (or communicating risks) before giving them prescriptions.
In a world where there are active initiatives aimed at building a system where all of us to chip in on healthcare costs for the collective (even more than we already do), then discussions about whether meds are needed or not (vs. if there's a better way) are reasonable and on the table for debate.

I'm receptive to the notion of universal single payer healthcare, but it comes with the stipulation that people need to at least put a half-[bless and do not curse][bless and do not curse][bless and do not curse][bless and do not curse][bless and do not curse] effort toward participating in their own health.

...same reason I wouldn't want to be in the same insurance pool as someone who says "Yeah, I'll start a bonfire in my basement...who cares, if the house burns down, State Farm will pay for it"
 
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RocksInMyHead

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In a world where there are active initiatives aimed at building a system where all of us to chip in on healthcare costs for the collective (even more than we already do), then discussions about whether meds are needed or not (vs. if there's a better way) are reasonable and on the table for debate.
By people with the knowledge to speak fluently on the subject, perhaps. But you're no more capable of judging my medical needs than I am of yours. It's one thing to say "Hey, I think it's a bit odd that I can get [drug] after a five minute video call with a doctor I've never talked to before" and another thing entirely to say "I don't think this person should get [drug] because I think there are other things they should be doing to treat their condition."

The first of those is an observation of a deviation from expected behavior - most of us are accustomed to needing to go to a doctor in-person, and perhaps develop a relationship with them before they start suggesting prescriptions. The second is a nuanced medical decision that requires detailed knowledge of the patient's medical history as well as a background in biology, chemistry, and pharmacology.

Democratizing technical fields is the stuff of communism parodies.
 
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ThatRobGuy

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By people with the knowledge to speak fluently on the subject, perhaps. But you're no more capable of judging my medical needs than I am of yours. It's one thing to say "Hey, I think it's a bit odd that I can get [drug] after a five minute video call with a doctor I've never talked to before" and another thing entirely to say "I don't think this person should get [drug] because I think there are other things they should be doing to treat their condition."

The first of those is an observation of a deviation from expected behavior - most of us are accustomed to needing to go to a doctor in-person, and perhaps develop a relationship with them before they start suggesting prescriptions. The second is a nuanced medical decision that requires detailed knowledge of the patient's medical history as well as a background in biology, chemistry, and pharmacology.

Democratizing technical fields is the stuff of communism parodies.
But what you're describing there is a form of credentialism (and a form that allows certain entrenched financial interests to carve what they want out of the system).

Where the people who do have the more in-depth knowledge (thereby, seen as the only ones qualified to "make the judgement call") are influenced to press down a specific path at the behest of other entities. In lay terms, if a certain group of people are deemed to be "the only ones who can make the call", and those are the same people who are perhaps getting some "perks" from the drug companies, then one has to wonder "do they really think this is the best approach?...or do they want to keep getting invited to those conferences at the resort?"


And I'd suggest there's a spectrum with regards to whether or not a person has to be deeply familiar with a subject to speak on absolutely all parts of it. There's levels to it. If it was subject about the nitty gritty of how electrical impulses control heart rhythm, then yeah, that's best left to a cardiologist. However, not every subject involving human health and nutrition is that complex and in-depth.

In same way that, yes, my mechanic knows a lot more about cars than I do, but I don't need to have the same level of prowess to accurately assess certain car problems, and to know that if after his meeting with the STP sales rep, he starts recommending expensive brake system flushes every 3,000 miles, that it sounds fishy.


Regarding diet/exercise/nutrition, it's one of the simpler concepts that's very approachable. So simple in fact, that they're able to teach it to school children (or at least they used to when I was in school, not sure what they're doing nowadays)


With regards to the concept of overprescribing, certain concepts can't be detached. In a world where commercials are blasting people with ads (with celebrity Cameos), and you walking into the waiting room that's littered with brochures for "if you think this sounds right for you, ask your doctor about <insert brand name drug here>", those are basically fostering an environment where we're not "deferring to the experts". The people with the power of the pen are being pressured in a certain direction.

"This is a decision between me and my doctor, he's the expert, so this was his call"... I'd call shenanigans on that, because that's not what's happening all the time, patients are specifically asking doctors for specific drugs that they heard about elsewhere (that they otherwise wouldn't have even known the name of).

The proof is in the pudding. Drug companies are spending billions and billions of dollars in advertising, telling patients which drugs to ask their doctors for before they even go in for the visit. And that spending has been steadily increasing over time. They wouldn't keep sinking that kind of money into advertising if they weren't getting a return on their investment.

In those scenarios, it's not actually a doctor's assessment in the true sense, it's a self-assessment with a compliant physician who's willing to grant the request.


Honest question, if there were no ads for GLP1 meds on TV/Facebook/Etc prompting people to go ask their doctor for it... Do you think the prescribing rate on those would have increased the way it has?
 
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RocksInMyHead

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But what you're describing there is a form of credentialism (and a form that allows certain entrenched financial interests to carve what they want out of the system).
There's nothing inherently wrong with "credentialism" - credentials exist for a reason.
And I'd suggest there's a spectrum with regards to whether or not a person has to be deeply familiar with a subject to speak on absolutely all parts of it. There's levels to it. If it was subject about the nitty gritty of how electrical impulses control heart rhythm, then yeah, that's best left to a cardiologist. However, not every subject involving human health and nutrition is that complex and in-depth.
In broad strokes, sure, but the question of whether or not an individual should be prescribed a particular medication is not broad strokes.
The proof is in the pudding. Drug companies are spending billions and billions of dollars in advertising, telling patients which drugs to ask their doctors for before they even go in for the visit. And that spending has been steadily increasing over time. They wouldn't keep sinking that kind of money into advertising if they weren't getting a return on their investment.
That's certainly a reasonable thing to point out, and I generally agree that there are issues with the amount of drug advertising we see in the US, but again, following that thread down to the individual goes beyond the capability of laypersons to evaluate.
 
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ThatRobGuy

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That's certainly a reasonable thing to point out, and I generally agree that there are issues with the amount of drug advertising we see in the US, but again, following that thread down to the individual goes beyond the capability of laypersons to evaluate.

But that's the thing, I'm not taking it down to the individual level for every single case. As I said in one of my very first posts in this thread, there are certainly people out there for whom, the pros of GLP-1s outweigh the cons.

The fact that we've seen a huge spike in prescriptions being handed out for it, and we've seen overprescribing trends for a wide variety of drugs over the past 30 years is evidence that it's happening, but I'm not suggesting that I know for certain which people are in those categories, just that we know it's happening.

If I said "Steve Shmedley living at 123 main street from Tacoma Washington definitely doesn't need them" that would be one thing, but I'm speaking more broadly.


...but it's impossible to have the discussion about the reality that "there's some people getting them prescribed to them who don't need them and would be better off modifying their diet", if people who are currently on them are going to take it way too personally. What logical conclusion does that lead to? We just let 100% of the population have them on-demand because anything less would be "gatekeeping weightloss" and evoke a "how dare you" response?


If, amid the opioid pandemic, someone pointed out "there's too many people getting prescriptions for those who don't need them, and would be better off trying other means like physical therapy" (which was 100% true speaking broadly), I got all hot and bothered and said "When my dad had stage 4 cancer, those drugs were the only thing that gave him relief at the end, so how dare you tell other people what they do and don't need, you're not a doctor!!!"

Would that have been a productive approach?
 
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RocksInMyHead

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But that's the thing, I'm not taking it down to the individual level for every single case.
Let me put it another way - a layperson can kibbitz on whether or not proper procedures are being followed. However, he is not qualified to determine whether or not people require professional services that he is not trained to provide.
The fact that we've seen a huge spike in prescriptions being handed out for it, and we've seen overprescribing trends for a wide variety of drugs over the past 30 years is evidence that it's happening, but I'm not suggesting that I know for certain which people are in those categories, just that we know it's happening.
This is kibbitzing on proper procedures.
...but it's impossible to have the discussion about the reality that "there's some people getting them prescribed to them who don't need them and would be better off modifying their diet", if people who are currently on them are going to take it way too personally. What logical conclusion does that lead to? We just let 100% of the population have them on-demand because anything less would be "gatekeeping weightloss" and evoke a "how dare you" response?
And this is determining whether or not people require professional services that you're not trained to provide.
 
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Tropical Wilds

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I think the other issue, beyond being in a fat phobic society or comparison envy (“why do I have to go to the gym when other people just get a shot?” As was said earlier), but profound ignorance on what the medications are and how they work. Going on the shot does lead to lifestyle changes. It does lead to different eating and exercise habits because how your body works is different. If people don’t do that then it simply doesn’t work.

Me, for example, I’m on it as an off-label medication to manage IBD. I didn't go on it to lose weight and honestly don’t have that much weight I can lose. As a result, I’ve lost only a little weight. My weight loss came not when I started the drug, but when I was well enough to start walking and running again. If I were to stop running, I’m sure any weight loss I had would plateau because my diet changes haven’t been that dramatic and because I’m not exercising. Even though I’m not losing weight, I had to still make lifestyle changes because of the medication. Earlier dinners, more fiber, more water, more protein, otherwise the side effects kill me. Adapting that has changed how my day goes.

Meanwhile my SIL has been on it for quite awhile and does have weight to lose, but she hasn’t lost a lot of weight because, despite not wanting to eat as much, she now drinks her calories by having she two 1,000 calorie drinks every day and she is not active. Her lifestyle has changed in that she’s managing the side effects, the expense, and the hassle, but she hasn’t done the rest of the work to lose any appreciable weight. And literally nobody is saying “take this shot and without any effort you will lose 100 pounds, no lifestyle change needed.”

The fact is when somebody had high blood pressure, we don’t say “change your diet because going on meds is lazy.” If one is anemic, we don’t say “taking iron is cheating, you should be eating more liver.” Nobody says “oh, you broke your leg after getting hit by a car while j-walking? Way to take the easy way out.” If people need it, want it, and their doctor signs off on it, they get a treatment or medication. The fact that people from the cheap seats get mad watching people they think they are better than have a bit of success shouldn’t be the driving factor or the value of a medication.
 
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rambot

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Yes a medication with a
What would be the nice way to say it?

"Some young people want to lose 15 lbs so they look better, but don't want to diet or exercise" isn't exactly flattering either. There are certain things that there's just no "super happy" way of saying.
You keep trotting out young people but that was all based on a link you gave from 2023.

Any new numbers will clearly show that it's gen X and boomers who are the big users.


I know literally nobody that who says "I'm just wanting to use 15 lbs or so" who isn't already eating really decent and exercising.

I know several very overweight people who are using it WITH lifestyle changes and are seeing improvement. Nothing is perfect but it's sure better and they see results faster with the GLP and that increases their motivation.
 
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