Who you pick fights with is irrelevant if we care about the truth.
The false idea here is that we are preaching Christianity, which is the gospel of Jesus Christ, by the persuasiveness and power of men as orators, and by our own cleverness to convince people.
If this is so, then we should abandon the faith of Christianity because it is a false religion. Rather Paul said:
My message and my preaching were not with wise and persuasive words, but with a demonstration of the Spirit's power, - 1 Corinthians 2:4
O Timothy, guard the deposit entrusted to you. Avoid the irreverent babble and contradictions of what is falsely called “knowledge,” - 1 Timothy 6:20
Beware lest anyone cheat you through philosophy and empty deceit, according to the tradition of men, according to the basic principles of the world, and not according to Christ. - Colossians 2:8
What is science itself?
https://en.wikipedia.org/wiki/Philosophy_of_science
It's philosophy. Philosophy is a set of axioms believed, and then upon which, you build reasoning. But the axioms of science in themselves are "according to the basic principles of the world" and not according to Christ who created and exists forever above the principles of this world.
So science is like a neat little toy, and people can have jobs with it. I am an accountant, and God condones it. But if I go turning my accounting into the philosophy of how to live my life, I am greatly sinning and it's wrong and evil.
Likewise, if science is the vehicle to arrive at truth, then you errored by Colossians 2:8. You are following a philosophy and not Christ. Christ is not a philosophy but a life with power, and a word of truth with miracles following.
Also in Noah's day, he cared about truth and he was the only man who did, along with his family. The rest of the world perished. Many back then could have said, "You're barking up the wrong tree, Noah." "Why preach that way Noah? It doesn't help your cause, it hurts it! Be more like us! Believe what we believe, then we will listen."
But the test for truth is not whether we are "picking the wrong fight". The test for truth, is Jesus Christ who is truth. And as Paul stated, the apostle to the gentiles, hand picked by the resurrected Jesus Christ himself, Paul states that philosophy according to the basic principles of this world, is an enemy of Christ, not acceptance of Christ.