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Discussion and Debate
Discussion and Debate
Physical & Life Sciences
Creation & Evolution
Is the Human Brain a Null Hypothesis for Darwinian Evolution?
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<blockquote data-quote="mark kennedy" data-source="post: 69638197" data-attributes="member: 29337"><p>Still playing the semantics game I see, let's work on the effect of mutations then we can tweek the terminology. Not really into the semantic hair splitting.</p><p></p><p></p><p></p><p>Not interested in E. coli, the subject is brain evolution and comparative genomics. Mutation rates might be of interest but it never gets that far, just gets dragged off on tangents like this one.</p><p></p><p></p><p></p><p>It's really irrelevant to the mutation rate. </p><p></p><p></p><p></p><p>Because most of them happen in parts of the genome where they don't effect genes. </p><p></p><p></p><p></p><p>I didn't say impossible, I said the vast majority are going to be deleterious assuming they actually have an effect and even beneficial ones have a low instance of fixation. Did you read the OP or just post random questions as they occurred to you? </p><p></p><p></p><p></p><p>They have to be or they are deleterious, the triple codon has to be preserved or you are looking at a frameshift. Your also assuming that the substitution is going to give you a functional amino acid that will also fold into a functional 3D protein. You have also failed to apply this to brain related genes, but we will get to that in time. </p><p></p><p></p><p></p><p>If you mean find a gene that is different in the Chimpanzee genome from a human gene, of course not. You seem to forget I am arguing for separate linage. If, on the other hand, you can find variant alleles in brain related genes in comparing human genomes to one another I'd be delighted to consider it. </p><p></p><p>As far as disproving my claims, you would first have to address them. We will wait and see if that happens.</p><p></p><p>Have a nice day <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /></p><p>Mark</p></blockquote><p></p>
[QUOTE="mark kennedy, post: 69638197, member: 29337"] Still playing the semantics game I see, let's work on the effect of mutations then we can tweek the terminology. Not really into the semantic hair splitting. Not interested in E. coli, the subject is brain evolution and comparative genomics. Mutation rates might be of interest but it never gets that far, just gets dragged off on tangents like this one. It's really irrelevant to the mutation rate. Because most of them happen in parts of the genome where they don't effect genes. I didn't say impossible, I said the vast majority are going to be deleterious assuming they actually have an effect and even beneficial ones have a low instance of fixation. Did you read the OP or just post random questions as they occurred to you? They have to be or they are deleterious, the triple codon has to be preserved or you are looking at a frameshift. Your also assuming that the substitution is going to give you a functional amino acid that will also fold into a functional 3D protein. You have also failed to apply this to brain related genes, but we will get to that in time. If you mean find a gene that is different in the Chimpanzee genome from a human gene, of course not. You seem to forget I am arguing for separate linage. If, on the other hand, you can find variant alleles in brain related genes in comparing human genomes to one another I'd be delighted to consider it. As far as disproving my claims, you would first have to address them. We will wait and see if that happens. Have a nice day :) Mark [/QUOTE]
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Is the Human Brain a Null Hypothesis for Darwinian Evolution?
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