Give every burden right now to God by faith--whatever it is that is bothering you: from guilt to annoying people you can't stop thinking about. Say: Thank you Jesus, I now, just by faith, am giving to you all my burdens. Thank you for receiving them off me. I now by faith, commit every area of my life to you, trusting that you want to bless me like you blessed Abraham, giving him both salvation, and abundance and peace in this life. I praise your goodness, Jesus!
Always walk in clear conscience (bad conscience ruins faith, which is the criteria for salvation, 1 Tim. 1:19), give all your guilt to Jesus by faith as a burden, receive His work of the cross, that already redeemed you from hell by Christ's blood, that had atoned for all your sin, i.e. for everything that can make you go to hell. If you lack faith in these things sometimes, repent a bit, and try receiving these things again, it should work, as God sometimes withholds our faith from us, so that we may start growing in Him, getting holier.
If it's bad and just doesn't go away, get drunk, do stuff your conscience is not letting you do, let loose for a bit--say to God you need it, that His commandment is not greater than man's dire need, for He said: Sabbath is for man and not man for the Sabbath. We sometimes need a vent like that, or our circuit can just blow.
I burnt out at one of my previous workplaces, working at a manufacturing facility, because I would bottle up harassment towards me. It took a week to recover, and now if anyone gets at me, I respond to them and put them on their right place. And when my conscience tells me: "what are you doing?", I say to God: commandment is for man and not man for commandment--I don't want to go have another nervous breakdown. And He receives it. Obviously though I try to be as meek as possible when I reply to God.