Ah, just for fun, since you're "done" with me....
Yeah? So? Who else would write an editorial, the accountant. It's still not a scientific article, just a commentary. As for the Journal. I've never heard of it (or published in it), I'll take your word for it that it is a good journal.
You've never heard of the BMJ? Really?
BMJ started out 180 years ago as a medical journal, publishing articles on stillborn children, amputation at the shoulder and the climate of the Isle of Wight.
Since 1840, BMJ has been publishing The BMJ, one of the world's four most cited general medicine journals. Today, we are a global brand with a strong vision for a healthier world.
www.bmj.com
Besides that, you're not really disputing the point of the editorial. In summary, it basically says that the public's expectations of an "effective" vaccine is not what was being studied. An "effective" vaccine to Pfizer meant we could stop your mild cough. But that's not at all how it was presented to the public.
Cough. Cough. Cough. (and a positive test)
Ah yes. The infamous nasal swab. Do you know what cycle count was required to be considered "positive" in this trial?
Are you familiar with Nobel-Prize winning inventor of the PCR test, Kary Mullis, who said:
"Anyone can test positive for practically anything with a PCR test, if you run it long enough with PCR if you do it well, you can find almost anything in anybody. It doesn’t tell you that you’re sick."
If you Google this statement, you'll likely end up at a USA Today "fact-check" saying this doesn't apply to COVID because the claim is "outdated" and was talking about HIV. The "fact-check" claims that the statement is "missing context" but doesn't really go on to explain what context would make this statement not applicable to COVID. You'd think the inventor of the PCR test would know better than a bunch of flunky "fact-checkers" at USA Today.
They were counting infections with and without the vaccine.
They were counting mild symptoms with and without the vaccine. You already confirmed that.
What? Are you denying COVID was serious?
As I recall about 1-2% of cases in the early phases (2020) DIED. That's about 10 times the fatality rate of annual flu (as opposed to the major pandemics like 1919) with 10-20 or so hospitalized per death for the flu. I don't recall the ratio for COVID19.
You're opening a whole new can of worms. The incompetent policies of sending patients infected with COVID out of hospitals and back to nursing homes to some of the most vulnerable populations all but assured that outcome. If you haven't seen it, I highly recommend the PBS documentary "Fire Through Dry Grass" which chronicles just how catastrophic NYC's policies on requiring nursing homes to accept COVID positive patients was for one nursing home.
www.firethroughdrygrass.com
These policies not only failed to protect the most vulnerable, they all but assured that mortality would be through the roof.
These studies take months and they couldn't predict where the latest outbreaks would be during the test.
And here we are again. The disease was bad. Real bad! So bad that we couldn't find a population that was large enough and sick enough to evaluate whether severe clinical outcomes would be improved. I sometimes wonder the level of cognitive dissonance one must possess to reconcile these two beliefs.
Sounds like a problem with a subset of the data, not the whole study, if accurate.
I'm sure it was just that one site. Everything was totally on the up-and-up, no doubt.
And if a subset of the data's integrity is flawed, it calls into question ALL of the data's integrity. Unless the problematic data is excluded, it's in your results calling into question the overall integrity of the data.
Because those *are* infections. The uninfected don't transmit.
Do the mildly infected transmit? We'll never know, because the study wasn't powered to find out.
No models needed. They were literally case numbers, hospitalizations, and deaths versus time plots. Once vaccines were wide spread the ratio of deaths and hospitaliztions to cases went way down. The effectiveness of the vaccinations against severe disease for the first few variants was clarly shown.
Until it wasn't. "The Pandemic of the Unvaccinated!™" was propagandized in the US until it was no longer possible to deny what nonsense that was. I'm certain you haven't read it, but I posted a study a few posts up that was talking about the "scapegoating" of the unvaccinated.
Short trials CANNOT show long-term results. So even if the mRNA shots provided an immediate benefit, it was incredibly transient. Worse, there are some studies that suggest that the more doses of vaccines you've had, the more LIKELY you are to get infected.
One particularly interesting study was done at the Cleveland Clinic that showed a perfect correlation between increased vaccine doses and increased infections.
Of course, the "fact-checkers" jumped into action after this study published claiming it didn't show what it clearly showed. But the study itself said this:
The association of increased risk of COVID-19 with more prior vaccine doses was unexpected. A simplistic explanation might be that those who received more doses were more likely to be individuals at higher risk of COVID-19. A small proportion of individuals may have fit this description. However, the majority of participants in this study were young, and all were eligible to have received ≥3 doses of vaccine by the study start date, which they had every opportunity to do. Therefore, those who received <3 doses (46% of individuals in the study) were not ineligible to receive the vaccine but rather chose not to follow the CDC's recommendations on remaining updated with COVID-19 vaccination, and one could reasonably expect these individuals to have been more likely to exhibit risk-taking behavior. Despite this, their risk of acquiring COVID-19 was lower than that that of participants those who received more prior vaccine doses.
Ours is not the only study to find a possible association with more prior vaccine doses and higher risk of COVID-19. During an Omicron wave in Iceland, individuals who had previously received ≥2 doses were found to have a higher odds of reinfection than those who had received <2 doses, in an unadjusted analysis [21]. A large study found, in an adjusted analysis, that those who had an Omicron variant infection after previously receiving 3 doses of vaccine had a higher risk of reinfection than those who had an Omicron variant infection after previously receiving 2 doses [22]. Another study found, in multivariable analysis, that receipt of 2 or 3 doses of am mRNA vaccine following prior COVID-19 was associated with a higher risk of reinfection than receipt of a single dose [7]. Immune imprinting from prior exposure to different antigens in a prior vaccine [22, 23] and class switch toward noninflammatory spike-specific immunoglobulin G4 antibodies after repeated SARS-CoV-2 mRNA vaccination [24] have been suggested as possible mechanisms whereby prior vaccine may provide less protection than expected. We still have a lot to learn about protection from COVID-19 vaccination, and in addition to vaccine effectiveness, it is important to examine whether multiple vaccine doses given over time may not be having the beneficial effect that is generally assumed.
In conclusion, this study found an overall modest protective effect of the bivalent vaccine against COVID-19 while the circulating strains were represented in the vaccine and lower protection when the circulating strains were no longer represented. A significant protective effect was not found when the XBB lineages were dominant. The unexpected finding of increasing risk with increasing number of prior COVID-19 vaccine doses needs further study.
Among 51 017 working-aged Cleveland Clinic employees, the bivalent coronavirus disease 2019 vaccine was 29% and 20% effective in preventing infection while the
academic.oup.com
Indeed, the "unexpected" finding in this and at least four other studies showing an increase of risk with an increase of doses does deserves further study. But who wants to be the one that comes out and says, "You know all those doses of vaccine you've been mandated to take? Yeah, each one makes you just a little more susceptible to infection than the last. But the good news is that even though you're more likely to get infected, you still have "an overall modest protective effect."
Now you're on to politics. I'm done with this and you.
Well, this is the political forum, and whether you like it or not, democrats and liberals were the ones that were vastly overestimating the risk that COVID-19 posed to most people. That's just the facts. The "desperation" you referenced was driven by the misinformation they believed and pushed concerning the risk of severe outcomes.