Of course, far all medications efficacy is never 100%, and adverse reactions will occur. The issue is the risk/benefit ratio. For the recommended vaccines, the evidence is very strong that the benefits vastly outweigh the risks.
It floors me when I hear the crackpot drivel about vaccines being a conspiracy by manufacturers and government to damage our health. Immunization is a way of life in the military. If the government knows vaccines are harmful, why on earth would they risk impairing the performance of soldiers?
I got the Hep B series in my 30s, when it was first released. I haven't had an HBAb titer done, but I've retired from practice, so my exposure risk is pretty low. But I get a flu shot every year, I got Zostavax, and Tdap, last year, and I just got Prevnar-13 a few months ago. I'll get Pneumovax next year. I'm not high-risk, so I shouldn't need any boosters.
The more controversial (and interesting) discussion is about Gardasil. The CDC just changed the recommendation. 11-12 year olds should now get 2 doses 6 months apart. Young people starting the series at ages 15-26 still need 3 doses. And boys should get it, too. What do you think?