In addition to the Trump Vaccines We now have a treatment.

hedrick

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:c

...I guess we're just regular then. :c
The US is very strong in the Pharma area. But we're definitely not the only ones. There are some concerns about the degree of haste in approval of Chinese and Russian vaccines, but there's a reasonable chance they'll work.
 
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timothyu

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Many treatments that show promise at an early stage don't end up being very helpful. The treatment has to go through clinical evaluations.
And financial assessments as to which is the most beneficial to the industry. We have to be realistic about this. These folks are not good samaritans
 
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timothyu

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The US is very strong in the Pharma area. But we're definitely not the only ones. There are some concerns about the degree of haste in approval of Chinese and Russian vaccines, but there's a reasonable chance they'll work.
It all goes back to who has the most connections with the WHO and WEF.
 
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loveofourlord

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And financial assessments as to which is the most beneficial to the industry. We have to be realistic about this. These folks are not good samaritans

They aren't why you will expect these things to eventually get approved. There is the whole nonsense about cancer cures not being profitable, except some new company that doesn't have skin in the game on selling treatment would make a fortune off of curing cancer and so on.
 
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timothyu

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There is the whole nonsense about cancer cures not being profitable,
The problem there isn't profit from a cure but the destruction of an entire industry and career researchers jobs once a cure is admitted to. The medical mafia isn't stupid.
 
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loveofourlord

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The problem there isn't profit from a cure but the destruction of an entire industry and career researchers jobs once a cure is admitted to. The medical mafia isn't stupid.

Right...neither are those that would make a fortune selling the cure.
 
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miamited

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How is it the United States comes up with 2 different vaccines, and a cure, and all other countries come up with ~ n-o-t-h-i-n-g.....

...Does that mean we're exceptional..? :)

Hi LC,

No, that means that you're one of those overly proud americans. You just don't pay attention to anything, or much care about anything, outside of the walls of your own nation. If you'd care to do some research, you'll find that there are quite a few nations working on vaccines. In fact, China is ahead of us.

China Is Inoculating Thousands With Unapproved COVID-19 Vaccines. Why?

Of course, they don't hold to the same standards of testing that we do, but they are a sovereign nation and that is their right. So, your claim that they've all come up with...nothing, just isn't a well informed statement.

God bless,
ted
 
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miamited

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Well they supposedly had a head start. But the question is why should the US be lagging behind. Fauci was funding Wuhan after all, so there must be some advantage there.

Hi timothy,

Uhh, you're going to have to provide some substantiating evidence that Dr. Fauci was somehow 'funding' Wuhan. Certainly our medical researchers have interest in some of what is going on in the Wuhan labs, but that the individual Dr. Fauci is somehow funding such an entity is likely just some Q-anon blabber. However, I'm certainly willing to look over any evidence you have. As I mentioned, China doesn't use the same testing procedures and protocols as our FDA does. Do consider that the first acronym in FDA stands for 'federal'... So, they don't have much to do with international drug research beyond just following it. But that allows China to rush new medicines to market faster than we do. Mexico is the same way. There are a lot of drugs you can buy in Mexico that haven't been given approval for use here in the U.S. But Mexico isn't beholden to follow the testing and approval standards of another nation. They can if they want, but they don't have to.

I'm not sure that one could substantiate that they had any head start. As far as I'm aware, the new coronavirus hit U.S. shores within a week or two of being identified in China. I imagine that the biggest difference is the testing standards. Now, will China have issues because they didn't test their vaccines as stringently or for as long as we did. Maybe. Time will tell. But it's also just as possible that our own vaccine will produce a few negative side effects. I mean we're still dealing with some side effects with many of our vaccines and medications that have been approved and on the market here for at least 50 years.

Do your research! Look up the history of approval and use of thalidomide. There are no guarantees that any nation's medical research is foolproof.

God bless,
ted
 
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timothyu

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JohnDB

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The OP says it worked on mice. So this is an early stage. Many treatments that show promise at an early stage don't end up being very helpful. The treatment has to go through clinical evaluations. That takes time.

Here's a list of current treatments. COVID-19 Treatments: An Updated List of Drugs and Medications in Development - GoodRx. It's quite likely that not all of them will turn out to be very helpful, or will help only a few patients in a specific group. E.g. it's not clear how useful Remdesivir actually is. The WHO has recently recommended against it.

But in the case of this particular science it's the mechanism that causes the cytokine storm that they are trying to stop...which they used already pre-approved drugs already in use for other things that they used in the research.

This speeds up the process dramatically for use as a "compassionate use" of a pharmaceutical. They tried the HCQ but it failed miserably. They tried Z-Packs...they failed too.

I'm not exactly sure what anti-inflammatory medicine they used. But apparently it worked in the fashion they wanted to stop the cytokine storm that causes so much of the damage they are wanting to avoid with patients.
 
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timothyu

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But in the case of this particular science it's the mechanism that causes the cytokine storm that they are trying to stop...which they used already pre-approved drugs already in use for other things that they used in the research.
A mechanism that has been around since the 80's big time and is behind the cytokine storm of CFS
 
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hedrick

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timothyu

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miamited

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Hi timothy,

From your reference: But just last year, the National Institute for Allergy and Infectious Diseases, the organization led by Dr. Fauci, funded scientists at the Wuhan Institute of Virology and other institutions for work on gain-of-function research on bat coronaviruses.

Yes, that's exactly what I said.
Certainly our medical researchers have interest in some of what is going on in the Wuhan labs,

Yes, American medical research into virology offers some funding for many such studies all over the world. The Wuhan labs have long been a leader in that effort. But that funding, per your evidence was for work on gain-of-function research on 'bat coronaviruses'. That isn't just Covid-19. Many, many of the outbreaks around the world in the past have found their beginnings in bat coronaviruses. Yes, the U.S. medical field has a great desire to gain understanding in how they leave their normal host and attack humans. No, that is not Dr. Fauci's money going to their research for such issues, but it is the monies doled out through hundreds of grants provided around the globe by the National Institute for Allergy and Infectious Diseases that has, for many, many years been awarded for research programs at various and sundry labs.

BTW, you'll note that in your own reference, the funding comes through the NIAID office. That funding is approved and appropriated by Congress. Here's a flow chart with explanations as to how NIAID funding for research is requested and approved: Background on NIAID Funding Opportunity Planning and the Budget Cycle. As you look over and read the accompaniment instructions and explanations, you'll find that the Director of the NIAID doesn't really have much to do with 'what' projects are approved for funding. Different groups fill out what are referred to as RFA's and these are submitted for consideration. Yes, Dr. Fauci is likely in on, and aware of, the various RFA's and may even put in a good word for a particular research project.

That funding doesn't mean that we will necessarily get first dibs on vaccines and such. Even if it did, we wouldn't just take a vaccine that had been created in a Chinese lab and put it on the streets in the U.S. As I said, our testing standards are a bit more stringent and we require certain time constraints on the work.

For example, in the U.S. a lab must go through 3 test phases and each one will take at least a couple of months for the development of possible side-effects to be manifest. These test phases are required by the CDC. They start off with a few dozen candidates in phase 1 and then each phase uses more candidates. Phase 3 can often include a few thousand candidates. But all of this takes time that vaccine manufacturers in China may not have to follow. So, they're able to bring a vaccine to market maybe a month or two faster than we can even if the research in both nations starts about the same time. Of course, the Chinese vaccine wont' be allowed to be used in the U.S. until it passes our CDC testing protocols.

Just to offer up some understanding as to how the funding actually works. BTW, it is worth noting that gain-of-function testing had been halted under the Obama administration and was one of the restrictions that Donald Trump removed in his glee to overturn everything that had President Obama's name on it. You want to blame somebody...blame Trump. LOL!

Finally, there is some talk that it may have been the gain-of-function studies that caused the virus to be released through some kind of lab accident. However, while there are a few scientists that believe this may have been the case, the majority of their peers find it a highly unlikely scenario.

In closing, Dr. Fauci did not provide funding. It was approved and provided by the U.S. Congress.

God bless,
ted
 
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JohnDB

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As a caution, take a look at An Explanation for Some Covid-19 Deaths May Not Be Holding Up. What I get from it (and I may we’ll have misunderstood) is that there’s more than one kind of cytokine storm, and it’s not clear whether it’s an actual problem or a symptom of the problem.

Correct...
But this went even further than that...

From the research paper:
Neutralizing TNF-α and IFN-γ protects against SARS-CoV-2, HLH, and sepsis in mice.

Two triggers for the cytokines.
That's what they were looking for...and there are particular antibodies that stop those particular ones. That's why this is good news. That already existing medications stop these triggers is even better.
 
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timothyu

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Two triggers for the cytokines.
That's what they were looking for...and there are particular antibodies that stop those particular ones. That's why this is good news. That already existing medications stop these triggers is even better.
Waiting to see how this will affect ME/CFS. They have gone silent this last week over this as it is funding season and like the stock market they don't want things to affect funding.
 
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