durangodawood
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- Aug 28, 2007
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2x Moderna. Felt some chills the evening of #2. Fine since.
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Whoosh over to P town on Cape Cod and see how all the vaccinated are doing.
Astra zenica for first, moderna for second, 4 weeks tomorrow :>
I think you're the first person I've heard of doing the "dose mixing" approach.
"Across the pond" I presume? (I heard UK and perhaps Canada were thinking about giving that a try)
I've heard mixed scientific opinions with regards to the pros & cons of dose mixing.
I guess the pros are that if one type is more effective on "strain A", and the other is more effective against "strain B", having different types could provide the benefit of more diverse "broad spectrum" immunity. (since one is a viral vector vaccine, the other is mRNA)
The potential concern I heard with that approach was that mRNA vaccines were thought to need two doses to provide the maximum amount of benefit (the way the doctor who administered my pfizer shots worded it as "the first dose is sort of a primer that makes the immune system aware of it...the second dose is what tells the immune system this is the second time we've seen this, time to step it up a notch!"
(which explains why people more commonly have a reaction to dose number 2 and not number 1)
But as more countries try the dose-mixing approach, I'd be interested to see how the results compare to sticking with one particular type.
I had my second Astra Zeneca last Monday with no after effects.
My first shot was 12 weeks ago. I had a mild headache on the morning after, which is unusual for me, so it may (or may not) have been vaccine related.
OB
Yeah I've wondered about that, my first shot was 3 day migraine, second was just tiredness that may be unrelated.Not sure if the concept has been thoroughly researched or not...
But I was watching an interview with an epidemiologist who suggest that if a person has a worse reaction to the first shot than the second, that may be an indication that they've already had the virus at some point. (like I said, take that for what it's worth, because I don't think the concept has been thoroughly researched yet)
The concept what "the immune system will have a stronger reaction to something it's encountered before and sees as a problem" (which is why many have a reaction after the second shot and not so much after the first). In essence, for people who've already had it, the first vaccine shot is, in a way, kind of like their "2nd shot".
Why vaccine side effects might be more common in people who've already had COVID-19
The research on it is still somewhat minimal, but the idea makes sense, in theory.
Not sure if the concept has been thoroughly researched or not...
But I was watching an interview with an epidemiologist who suggest that if a person has a worse reaction to the first shot than the second, that may be an indication that they've already had the virus at some point. (like I said, take that for what it's worth, because I don't think the concept has been thoroughly researched yet)
The concept what "the immune system will have a stronger reaction to something it's encountered before and sees as a problem" (which is why many have a reaction after the second shot and not so much after the first). In essence, for people who've already had it, the first vaccine shot is, in a way, kind of like their "2nd shot".
Why vaccine side effects might be more common in people who've already had COVID-19
The research on it is still somewhat minimal, but the idea makes sense, in theory.