I don't watch the Bigest Loser show but I saw this on another forum and found it to be encouraging
http://www.nbc.com/The_Biggest_Loser/dietcenter/got_milk/dr_jens_journal-wk7.shtml
PCOS is quite common -- about 6-8% of women have it, and a whopping 28% of overweight/obese women have it!
PCOS has been rumored to make weight loss more difficult, but there are no scientific studies to prove this! However, many scientific studies HAVE been done to show that a lower-calorie diet and exercise DO induce weight loss in women with PCOS, and that this weight loss (even just 5 or 10% of body weight) can ameliorate many of the negative aspects of the syndrome: it can lead to restoration of ovulation and fertility, decreases in male hormone levels, and improvements in insulin function and diabetes.
As an example, our own Julie Hadden, one of the black team members, has PCOS -- she had a slow start, but has been just as successful as the other Biggest Loser contestants at fat loss through calorie-counting and exercise.
In particular, building muscle through strength training may help increase metabolism in women who feel that they might be disadvantaged from a metabolic standpoint.
http://www.nbc.com/The_Biggest_Loser/dietcenter/got_milk/dr_jens_journal-wk7.shtml