Could CRISPR work on a virus?

sfs · Apr 15, 2020

mindlight said:
Now for my idiot question: but I have to know. How would a CRISPR detector work? Of course I want to see a non invasive Star Trek tricorder but I suspect you take a sample of blood or something and put it into a mobile machine of some sort. Is that right? How big is the machine. One day could you put it into your pocket and could the same machine having analysed the sample, perhaps in synch with larger computers elsewhere, process a antiviral response that could then be injected back into the person using the raw material of the sample given. Could that one day work in minutes rather than hours?

I would rather not speculate -- as I said, it's not my field.

sfs · Apr 15, 2020

Cimorene said:
Whoa you work for that lab?

That lab and this lab. I split my time. (This is me, by the way.)

Ok THIS is totally why Ella & I had suggested a section for coronavirus or public health bc there's ppl like you that could give totally solid info for it that could be easy to find. I mean I pretty much never come here anymore so it was just random I saw this 1 post, otherwise I never would have. Maybe you could ask & they'd listen to you.

I'm not sure that would change much -- there would be just as much noise, and discussions would still drift into COVID-19 territory in other forums.

Subduction Zone · Apr 15, 2020

Okay, I am clearly out of any expertise on this subject. So even though CRISPR could target the virus in the body I assume that it could not target the virus once inside a cell. Is that correct?

sfs · Apr 15, 2020

Subduction Zone said:
Okay, I am clearly out of any expertise on this subject. So even though CRISPR could target the virus in the body I assume that it could not target the virus once inside a cell. Is that correct?

It's not going to do much outside of cells, since virus particles are wrapped in protein and sometimes a lipid envelope. As I noted in one earlier post above, the hard part is getting the necessary components inside the cells. There are ways of doing that -- of delivering macromolecules into cells -- but they need further development. The ones I know of are modified viruses and engineered nanoparticles.

HitchSlap · Apr 15, 2020

Tinker Grey said:
And, of course, what about viruses?

I heard all you have to do is blow on 'em.

Cimorene · Apr 16, 2020

sfs said:
That lab and this lab. I split my time. (This is me, by the way.)

I'm not sure that would change much -- there would be just as much noise, and discussions would still drift into COVID-19 territory in other forums.

That's really cool. You're probably right. Every other site I ever go to has info about coronavirus pinned to help ppl. This one has conspiracy theories about the coronavirus that have hurt ppl featured. It's why I can't come much bc anymore bc that feels so so so wrong to me but then I see posts like yours & I do feel better there's some good here.

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Could CRISPR work on a virus?

sfs

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Subduction Zone

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sfs

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