Projecting hospital utilization during pandemic in the USA

Ophiolite

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Most of the threads regarding the Covid-19 pandemic, with several honourable exceptions, seem to have been low on facts and high on rhetoric, speculation and opinion. The linked research paper, Projecting hospital utilization during the COVID-19 outbreaks in the United States, published in PNAS, may go some way to redressing the balance.

Abstract:
In the wake of community coronavirus disease 2019 (COVID-19) transmission in the United States, there is a growing public health concern regarding the adequacy of resources to treat infected cases. Hospital beds, intensive care units (ICUs), and ventilators are vital for the treatment of patients with severe illness. To project the timing of the outbreak peak and the number of ICU beds required at peak, we simulated a COVID-19 outbreak parameterized with the US population demographics. In scenario analyses, we varied the delay from symptom onset to self-isolation, the proportion of symptomatic individuals practicing self-isolation, and the basic reproduction number R0. Without self-isolation, when R0 = 2.5, treatment of critically ill individuals at the outbreak peak would require 3.8 times more ICU beds than exist in the United States. Self-isolation by 20% of cases 24 h after symptom onset would delay and flatten the outbreak trajectory, reducing the number of ICU beds needed at the peak by 48.4% (interquartile range 46.4–50.3%), although still exceeding existing capacity. When R0 = 2, twice as many ICU beds would be required at the peak of outbreak in the absence of selfisolation. In this scenario, the proportional impact of self-isolation within 24 h on reducing the peak number of ICU beds is substantially higher at 73.5% (interquartile range 71.4–75.3%). Our estimates underscore the inadequacy of critical care capacity to handle the burgeoning outbreak. Policies that encourage self-isolation, such as paid sick leave, may delay the epidemic peak, giving a window of time that could facilitate emergency mobilization to expand hospital capacity.

Significance:
Our results highlight that the growing coronavirus disease 2019 (COVID-19) outbreak in the United States could gravely challenge the critical care capacity, thereby exacerbating case fatality rates. In the absence of a preventive vaccine, efforts to contain the outbreak, such as improving self-isolation rates and encouraging better hygiene practices, can alleviate some of the pressures faced by the healthcare system during an outbreak. Both emergency expansion of hospital facilities to treat COVID19 and government appropriations to facilitate voluntary case isolation are urgently needed
 
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com7fy8

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In Massachusetts, I have kept a daily total of new cases and deaths. The governor has said the thing would peak later than now. But already the new case numbers are going down. And each of these lower daily number totals were maybe about five days or more since social distancing started here.

So, I see it is possible things could get better, even sooner. But we will have to see, of course.

Officials seem to be saying they do not expect to stop the problem, but at least social distancing can slow things down so hospitals are less strained. But in Massachusetts now they are saying they are preparing more space than they think will be necessary, in supplemental buildings.

And they flew the Patriot's plane to China to get masks, after someone confiscated their order in New York City. But they sent some of their masks to New York.
 
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Halbhh

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In Massachusetts, I have kept a daily total of new cases and deaths. The governor has said the thing would peak later than now. But already the new case numbers are going down. And each of these lower daily number totals were maybe about five days or more since social distancing started here.

So, I see it is possible things could get better, even sooner. But we will have to see, of course.

Officials seem to be saying they do not expect to stop the problem, but at least social distancing can slow things down so hospitals are less strained. But in Massachusetts now they are saying they are preparing more space than they think will be necessary, in supplemental buildings.

And they flew the Patriot's plane to China to get masks, after someone confiscated their order in New York City. But they sent some of their masks to New York.
It's good to be aware that we've tended to see ups and downs in daily new cases at times, especially during Saturday to Monday leveling off or going down a bit, and then going back up Tuesday (which number isn't very well close to it's reading until after midnight some time, or later). I remember this especially with Italy, where it looked to me at one point 3 weeks ago like they had bent the curve, but it was too soon actually to reach that conclusion. That's why officials are cautious -- they have good reason to be cautious before claiming it's leveling (to a roughly continuing same number of new cases every day, before a decline later). You need about 5 days really to feel confident.

See 2nd graph here:
Italy Coronavirus: 132,547 Cases and 16,523 Deaths - Worldometer
 
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Halbhh

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Most of the threads regarding the Covid-19 pandemic, with several honourable exceptions, seem to have been low on facts and high on rhetoric, speculation and opinion. The linked research paper, Projecting hospital utilization during the COVID-19 outbreaks in the United States, published in PNAS, may go some way to redressing the balance.

Abstract:
In the wake of community coronavirus disease 2019 (COVID-19) transmission in the United States, there is a growing public health concern regarding the adequacy of resources to treat infected cases. Hospital beds, intensive care units (ICUs), and ventilators are vital for the treatment of patients with severe illness. To project the timing of the outbreak peak and the number of ICU beds required at peak, we simulated a COVID-19 outbreak parameterized with the US population demographics. In scenario analyses, we varied the delay from symptom onset to self-isolation, the proportion of symptomatic individuals practicing self-isolation, and the basic reproduction number R0. Without self-isolation, when R0 = 2.5, treatment of critically ill individuals at the outbreak peak would require 3.8 times more ICU beds than exist in the United States. Self-isolation by 20% of cases 24 h after symptom onset would delay and flatten the outbreak trajectory, reducing the number of ICU beds needed at the peak by 48.4% (interquartile range 46.4–50.3%), although still exceeding existing capacity. When R0 = 2, twice as many ICU beds would be required at the peak of outbreak in the absence of selfisolation. In this scenario, the proportional impact of self-isolation within 24 h on reducing the peak number of ICU beds is substantially higher at 73.5% (interquartile range 71.4–75.3%). Our estimates underscore the inadequacy of critical care capacity to handle the burgeoning outbreak. Policies that encourage self-isolation, such as paid sick leave, may delay the epidemic peak, giving a window of time that could facilitate emergency mobilization to expand hospital capacity.

Significance:
Our results highlight that the growing coronavirus disease 2019 (COVID-19) outbreak in the United States could gravely challenge the critical care capacity, thereby exacerbating case fatality rates. In the absence of a preventive vaccine, efforts to contain the outbreak, such as improving self-isolation rates and encouraging better hygiene practices, can alleviate some of the pressures faced by the healthcare system during an outbreak. Both emergency expansion of hospital facilities to treat COVID19 and government appropriations to facilitate voluntary case isolation are urgently needed
About the last sentence, it's interesting to hear in Governor Cuomo's briefings over the last week, and especially today -- they've been really informative about how NY is dynamically allocating resources across the state. (The daily briefings can be found on youtube).
 
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com7fy8

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we've tended to see ups and downs in daily new cases at times
Well, each day can have different numbers of tests reported as done. More tests could result in more cases reported. So, numbers maybe have something to do with how many tests have been done. So, in a way higher numbers could be better . . . if they mean the health workers have been more successful at finding who is infected. And days simply can be different.
 
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