The 4th seal = Death (Which is the martyrdom of the saints and others by the Antichrist by the enforcement of the Mark).
The 5th seal = The recently martyred saints cry out for justice up in Heaven under the alter of God.
The 6th seal = God responding to the martyred saints cry for justice by bring in the Day of Wrath or the Day of the Lord to punish the devil, the Antichrist, and it's world system once and for all (concluding with the return of our Lord destroying the nations and this Earth being purified by fire similar to the global flood but far more effective at erasing the previous civilization).
The Day of the Lord will not happen until the man of sin shows himself in the temple that he is god.
The Day of the Lord is a period of time of vengeance and the finishing up of justice upon this world.
The Day of the Lord begins with the breaking of the 6th seal because the signs of both the (a) Day of the Lord and (b) the 6th seal show the sun turning black and the moon turning blood red. See my bolded highlighted colored words in blue and red in the verses below.
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Signs Leading Up to the Day of the Lord:
The Sixth Seal:
(Part 1 - Sun goes dark, moon turns blood red, and a great earthquake, etc.):
(After These Signs The Days of Vengeance Ends):
The Sixth Seal Opened:
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Revelation 6:12-13
And I beheld when he had opened
the sixth seal, and, lo, there was a great earthquake; and
the sun became black as sackcloth of hair, and the moon became as blood; And the stars of heaven fell unto the earth, even as a fig tree casts its unripe figs, when it is shaken by a mighty wind.
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Matthew 24:29-30a
Immediately after the tribulation of those days shall the sun be darkened, and the moon shall not give her light, and the stars shall fall from heaven, and the powers of the heavens shall be shaken: And then shall appear the sign of the Son of man in heaven:
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Mark 13:24-25
But in those days, after that tribulation, the sun shall be darkened, and the moon shall not give her light, And the stars of heaven shall fall, and the powers that are in heaven shall be shaken.
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Luke 21:25-26
And there shall be signs in the sun, and in the moon, and in the stars; and upon the earth distress of nations, with perplexity; the sea and the waves roaring; Men's hearts failing them for fear, and for looking after those things which are coming on the earth: for the powers of heaven shall be shaken.
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Acts 2:20
The sun shall be turned into darkness, and the moon into blood, before that great and notable day of the Lord come:
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Joel 2:31
The sun shall be turned into darkness, and the moon into blood, before the great and the terrible day of the LORD come.
Admonishments on the "Day of the Lord" before the "Second Coming":
(A clue on when Day of the Lord will occur and a warning against desiring it):
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2 Thessalonians 2:1-2 NLT
Now, dear brothers and sisters, let us clarify some things about the coming of our Lord Jesus Christ and how we will be gathered to meet him. Don’t be so easily shaken or alarmed by those who say that the day of the Lord has already begun.
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2 Thessalonians 2:3
Let no man deceive you by any means: for that day shall not come, except there come the falling away first, and that man of sin be revealed,
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Amos 5:18
Woe unto you that desire the day of the LORD! to what end is it for you? the day of the LORD is darkness, and not light.
The Day of the Lord (The Day of Wrath):
(The Great Tribulation Continued):
Description of the Day of the Lord:
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Zephaniah 1:14-15
The great day of the LORD is near, it is near, and hasteth greatly, even the voice of the day of the LORD: the mighty man shall cry there bitterly. That day is a day of wrath, a day of trouble and distress, a day of wasteness and desolation, a day of darkness and gloominess, a day of clouds and thick darkness,
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Zechariah 14:1 NLT
Watch, for the day of the LORD is coming when your possessions will be plundered right in front of you!
The Day of the Lord Begins:
(The Great Day of Wrath):
The Sixth Seal: (Part 2)
(Closing Scene in Heaven #1: God the Son appears to the Earth sitting upon a Throne):
Conclusion of the Sixth Seal:
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Revelation 6:14-17
And the heavens departed as a scroll when it is rolled together; and every mountain and island were moved out of their places. And the kings of the earth, and the great men, and the rich men, and the generals , and the mighty men, and every slave, and every free man, hid themselves in the dens and in the rocks of the mountains; And said to the mountains and rocks, Fall on us, and hide us from the face of him that sits on the throne, and from the wrath of the Lamb:
For the great day of his wrath has come; and who shall be able to stand?
Note: The "great day of his wrath" is also just another way of saying the "Day of the Lord" which is a period of time of vengeance starting at the 6th seal and ending with the return of Jesus destroying the nations and this world being purified with fire so that the Millennium can then begin (with Christ ruling).