I would say yes, only because my ex-wife had no respect for me whatsoever.
Here's the rub: western culture has made "submission" into a dirty word because the secular world has associated it with bondage, slavery, and in recent decades all kinds of psycho-sexual connotations.
So, right or wrong, I think the synonym "deference" gets the point across where "submission" causes people's minds to drift into inappropriate areas. Both sides need to respect the other, as well as love the other. If either of those elements are lacking it crumbles pretty quick. I can't emphasize enough how emasculated and disrespected I felt when my ex-wife would regularly ignore my wishes, my advice, my decisions and either do whatever she wanted to do in the first place, or go and get a second opinion from her parents and then act according to that. I was never the final word on anything that involved more than just me. Lo and behold, our marriage barely lasted four years. I'm not saying that was the sole reason it failed, but it was a big one.
At some level, I want my wife to defer to me on issues of the family. I'm capable of acknowledging a woman's wisdom, knowledge, and expertise on a given issue and can consider it or defer to her if I think it's appropriate. But I need her to trust me. If I've married her that means I love her, and if I love her that means I would move the world for her. So I would hope that she trusts me to lead her and our family in an upright manner.
Beyond that, to me a Godly wife is a woman who conforms completely and totally to the teachings of the Catholic Church and finds full satisfaction in Christ, the Sacraments and the life of the Church that He and His Apostles have left us.