stevevw
inquisitive
I am saying if mutations are basically an error in what is already working good then a so called beneficial mutation runs against this and therefore will not be prominent as benefit doesn't come from an error normally and errors dont normally make better and fitter life. So these beneficial mutations are either perceived as benefits but the complete effects are not considered which may turn out to be a non benefit in reality. Or the mutations are so slight that any benefit is not fixed on its own and therefore is not selected in the first place. To have a benefit they would need to become more prominent by adding more beneficial mutations. But for this to happen they would need to be all adding up to the same benefit in function from a blind process which seems unlikely. The chances are the benefit will be missed and any benefit isolated will not be selected.What mechanism are you proposing which would consistently filter out mutations that even you admit are beneficial?
As one of the papers has shown even beneficial mutations can cause each other to have diminishing returns when accumulated through negative epistasis rather then adding up to contribute to the specific building that protein folds require to be functional and fit. The space for functional protein sequences is very narrow and the space for non function is very wide that the odds are massive for creating the specific folds needed. So logic tells you that a blind proceed is going to miss the mark even with time. But even if we allow some to get through the amount needed for making all of life would need a massive amount of beneficial mutations that hit a finite mark time and time again and need more time then the existence of earth being around. To accommodate that many rare beneficial mutations would need to also include an awful lot of negative ones which from the evidence seems to show that there are more negative mutations than beneficial ones. That would mean life having to accommodate too many negative mutations which would make life less fit in the end.
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