Cannabis compound inhibits SARS-CoV-2 replication in human lung cells

jayem

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Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells...

Marsha Rosner from the University of Chicago in Illinois and colleagues found that cannabidiol (CBD) and its metabolite 7-OH-CBD potently blocked SARS-CoV-2 replication in lung epithelial cells...

Interesting. The anti-viral effect was only seen with cannabidiol and the 7-hydroxy-CBD metabolite. Other cannabinoids, like THC, lacked this property. It remains to be seen if CBD can actually treat patients who are already infected with SARS-CoV-2, and are symptomatic.

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells
 

FrumiousBandersnatch

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Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells...

Marsha Rosner from the University of Chicago in Illinois and colleagues found that cannabidiol (CBD) and its metabolite 7-OH-CBD potently blocked SARS-CoV-2 replication in lung epithelial cells...

Interesting. The anti-viral effect was only seen with cannabidiol and the 7-hydroxy-CBD metabolite. Other cannabinoids, like THC, lacked this property. It remains to be seen if CBD can actually treat patients who are already infected with SARS-CoV-2, and are symptomatic.

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells
Interesting - there's scope for a survey of people inhaling the lower THC cannabis varieties in states where it's legal. Maybe mellow weed is protective ;)
 
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timothyu

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Interesting - there's scope for a survey of people inhaling the lower THC cannabis
Not really considering hemp and marijuana are the same family but two entirely different plants and opposite in nature, like tomatoes and nightshade.
 
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sesquiterpene

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Researchers in the United States have conducted a study showing that a cannabis plant compound inhibited infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human lung cells...

Marsha Rosner from the University of Chicago in Illinois and colleagues found that cannabidiol (CBD) and its metabolite 7-OH-CBD potently blocked SARS-CoV-2 replication in lung epithelial cells...

Interesting. The anti-viral effect was only seen with cannabidiol and the 7-hydroxy-CBD metabolite. Other cannabinoids, like THC, lacked this property. It remains to be seen if CBD can actually treat patients who are already infected with SARS-CoV-2, and are symptomatic.

Cannabis compound inhibits SARS-CoV-2 replication in human lung cells
Interesting enough, but note that the human lung cells tested weren't actually in human lungs at the time, which is a really important distinction. These drugs have moderate activity - low micromolar - concentrations though, which might actually be obtainable in humans. They tried to compare actual cases of Covid in people who were already using CBD vs. case controls, but they didn't have enough to get good statistics on, and case-control studies are somewhat shaky in general. Are their results interesting enough to warrant a high quality clinical trial? We'll have to see.
 
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timothyu

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Are their results interesting enough to warrant a high quality clinical trial? We'll have to see.
True but in the meantime does it hurt to have a bottle in the medicine cabinet for all sorts of uses?
 
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Tanj

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True but in the meantime does it hurt to have a bottle in the medicine cabinet for all sorts of uses?

Sure. We could market it under the brand name "Snake Oil"
 
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Landon Caeli

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Not really considering hemp and marijuana are the same family but two entirely different plants and opposite in nature, like tomatoes and nightshade.

True, though "marijuana" is just the Spanish term for cannabis.

...English speakers should call it cannabis.
 
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Tanj

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timothyu

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True, though "marijuana" is just the Spanish term for cannabis.
Cannabis is the name of the plant family, but the related species within are all different. For instance hemp is primarily CBD while marijuana is THC. Hemp out in the real world is farmed legally everywhere for it usefulness and medicinal properties. Marijuana however is either illegal to grow or allowed only under specific conditions because of it's 'narcotic' potential. There is a reason the world knows the two plants to be different while the US made a law to call them the same plant. That may change as the petroleum industry dies and farmers can switch from corn to hemp to fuel the nation. Hemp once fueled and lubricated vehicles, was used to manufacture vehicle bodies, clothes rope and all sorts of things the petrol industry felt threatened by in it's infancy. Heaven forbid these moguls would have to stop claiming what was in the ground as theirs alone and go back to paying farmers for their produce. If that changed only the canola moguls would be threatened.
 
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Landon Caeli

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Cannabis is the name of the plant family, but the related species within are all different. For instance hemp is primarily CBD while marijuana is THC. Hemp out in the real world is farmed legally everywhere for it usefulness and medicinal properties. Marijuana however is either illegal to grow or allowed only under specific conditions. There is a reason the world knows the two plants to be different while the US mad a law to call them the same plant. That may change as the petroleum industry dies and farmers can switch from corn to hemp to fuel the nation.

I agree, I just don't like the term "marijuana"... Unless it can be pronounced [mari-joo-ana], because in English, the letter "J" does not sound like an "H".

...It should be universally referred to as Cannabis by English speakers for this reason. And typically is.
 
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timothyu

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..It should be universally referred to as Cannabis by English speakers for this reason.
Is it right to label differing species under one name even though their properties are totally different? Or should each be recognized on their own merit where the name cannabis remains the surname of the plant family?
 
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Landon Caeli

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Is it right to label differing species under one name even though their properties are totally different? Or should each be recognized on their own merit where the name cannabis remains the surname of the plant family?

But "marijuana" isn't a real word. It's just a Spanish slang word invented in Mexico.

...Here in the United States we call hemp, and other non THC Cannabis plants "schwag", or "ditchweed" (English slang). We consider everything else Cannabis.
 
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timothyu

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Here in the United States we call hemp, and other non THC Cannabis plants "shwag", or "ditchweed" (English slang). We consider everything else Cannabis.
Well at least you separate the two in distinction
 
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Ponderous Curmudgeon

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But "marijuana" isn't a real word. It's just a Spanish slang word invented in Mexico.

...Here in the United States we call hemp, and other non THC Cannabis plants "schwag", or "ditchweed" (English slang). We consider everything else Cannabis.
I don't know how old you are but even my kids would say "no"
 
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FrumiousBandersnatch

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Not really considering hemp and marijuana are the same family but two entirely different plants and opposite in nature, like tomatoes and nightshade.
Who said anything about hemp? The article was about cannabidiol, which is present in marijuana (sativa particularly) - I mentioned lower THC varieties because the varieties bred for high potency THC (skunk type) have significantly reduced levels of other cannabinoids.
 
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FrumiousBandersnatch

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True, though "marijuana" is just the Spanish term for cannabis.

...English speakers should call it cannabis.
In the UK, they're often used interchangeably, although marijuana generally refers to the bud and leaf, and cannabis to the resin itself.

In botanical use, cannabis refers to the plant.
 
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FrumiousBandersnatch

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How so, exactly? Have they done the 10-20 year extensive studies on this compound that vaccines are supposed to have? I mean, what about the long term effects!!

A common herbal medicine may cause liver cancer mutations | New Scientist
The long term evidence suggests that cannabis use is relatively safe (vaping rather than smoking), and the issues with cannabis psychosis result from the breeding of ultra-high THC varieties with minimal CBD. In more balanced strains, the CBD has an anti-psychotic effect, countering the potential dangers of THC alone.
 
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