Mark, it would have helped if you had read, and perhaps quoted, the end of the abstract for that first paragraph:First of all I was using the term transcription error in a list of mutations, your cohort insisted that transcription errors were not mutations:
Phenotypic mutations (errors occurring during protein synthesis) are orders of magnitude more frequent than genetic mutations. Consequently, the sequences of individual protein molecules transcribed and translated from the same gene can differ. Potential role of phenotypic mutations in the evolution of protein expression and stability
In contrast, errors that occur during RNA transcription are considered transient, because the life span of mRNAs and their encoded proteins is thought to be too short to have heritable consequences. Transcriptional Infidelity Promotes Heritable Phenotypic Change in a Bistable Gene NetworkThat's all that really amounted to and of course it turned into the error mining ad hominem attack that evolutionists are obsessed with. I simply insisted that transcript errors are mutations because they are, actually including them in a list of mutations. I suppose it's a nice diversion to keep harping on a semantical issue since it's a lot easier then actually discussing substantive issues, like.....I don't know....intelligent design.
"Thus, although phenotypic mutations are not individually subjected to inheritance and natural selection, as are genetic mutations, they collectively exert a direct and immediate effect on protein fitness. They may therefore play a role in shaping protein traits such as expression levels, stability, and tolerance to genetic mutations. "
When discussing evolution vs ID, don't you think that part is important? Errors in translation of proteins can't be passed down from generation to generation, which is why they are not listed as "mutations" when discussing evolution.
In the paper, the authors did use a genetic mutation: "To test the effects of such mutations, we established a bacterial system in which an antibiotic resistance gene (TEM-1 β-lactamase) was transcribed by either a high-fidelity RNA polymerase or its error-prone mutant. "
The "error-prone" RNA polymerase was a genetic mutant. The TEM-1 beta-lactamase proteins produced by the error-prone mutant are not all going to be the same.
What the authors found was that, in some circumstances, having a genetic mutation in RNA polymerase promoted the survival of individuals that had TEM-1 beta lactamase variations that were more stable. IOW, it selected individuals with mutations in the beta-lactamase gene such that even the proteins produced by erroneous transcription had activity.
I don't see any support here for ID. In fact, I see further refutation of ID and support for evolution, since it shows natural selection in action.
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