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What follows are from over ten years of study of the comparative studies related to human brain evolution. Comparative Genomics should have ended, or at least challenged, Darwinian evolution by now but it is exalted above all skepticism. The a priori assumption of universal common descent is immutable in modern philosophies of natural history. The reason they are not isn't the weight of the evidence indicating chimpanzee-human common ancestry, but the animosity toward anything remotely theistic being suggested as a cause:
This grand theatrical production has been performing for over a century now, it's history littered with fabrication. Perhaps the longest running demonstration was easily the Piltdown fraud. The Piltdown Hoax was the flagship transitional of Darwinism for nearly half a century and it was a hoax. A skull taken from a mass gravesite used during the Black Plague matched up with an orangatan jawbone. Even Louise Leakey, the famous paleontologist has said that jaw didn’t belong with that skull so people knew, long before it was exposed, that Piltdown was contrived.
The problem was that there was nothing to replace it as a transitional from ape to man. Concurrent with the prominence of the Piltdown fossil Raymond Dart had reported on the skull of an ape that had filled with lime creating an endocast or a model of what the brain would have looked like. Everyone considered it a chimpanzee child since it’s cranial capacity was just over 400cc but with the demise of Piltdown, a new icon was needed in the Darwinian theater of the mind. Raymond Dart suggests to Louis Leakey that a small brained human ancestor might have been responsible for some of the supposed tools the Leaky family was finding in Africa. The myth of the stone age ape man was born.
The Scottish anthropologist Sir Arthur Keith had built his long and distinguished career on the Piltdown fossil. When it was exposed it sent Darwinians scrambling, Arthur Keith had always rejected the Taung Child (Raymond Dart’s discovery) a chimpanzee child. Rightfully so since it’s small even for a modern chimpanzee. Keith would eventually apologized to Dart and Leakey would take his suggested name for the stone age ape man, Homo habilis, but there was a very real problem. The skull was too small to be considered a human ancestor, this impasse became known as the Cerebral Rubicon and Leakey’s solution was to simply ignore the cranial capacity.
Ever notice that there are no Chimpanzee ancestors in the fossil record? That’s because every time a gracial (smooth) skull, that is dug up in Asian or Africa they are automatically one of our ancestors.
These two are the only Hominid fossils I've seen that are really being passed of as transitional. They both have chimpanzee size brains, with all the features one would expect of a knuckle dragging, tree dwelling ape. What is far more important then finding something indicating a transitional fossil, which they have failed to do, is to understand what the basis of the three-fold of the human brain from that of apes:
That was probably the broadest comparison of brain related genes between apes and humans shortly after the unveiling of the findings of the Human Genome Project in 2001. Since then they have discovered at least two dramatic giant leaps that would have had to occur in order of the human brain to have emerged from ape like ancestors SRGAP2, HAR1F. In addition genes involved with the development of language (FOXP2), changes in the musculature of the jaw (MYH16) , and limb and digit specializations (HACNS1).
Of course Creationists have their opinions about this gene:
In one of the areas of the human genome that would have had to change the most, Human Accelerated Region (HAR), we find a gene that has changed the least over just under 400 million years HAR1F. Just after the Cambrian is would have had to emerge de novo, fully formed, fully functional and permanently fixed along broad taxonomic categories. In all the time since it would allow only two substitutions, then, while the DNA around it is being completely overhauled it allows 18 substitutions in a regulatory gene only 118 nucleotides long. The vital function of this gene cannot be overstated:
This all has to occur after the chimpanzee human split, while our ancestors were contemporaries in equatorial Africa, with none of the selective pressures effecting our ancestral cousins. This is in addition to no less then 60 de novo (brand new) brain related genes with no known molecular mechanism to produce them. Selection can explain the survival of the fittest but the arrival of the fittest requires a cause:
Whatever you think happened one thing is for sure, random mutations are the worst explanation possible. They cannot produce de novo genes and invariably disrupt functional genes. You can forget about gradual accumulation of, 'slow and gradual accumulation of numerous, slight, yet profitable, variations' (Darwin). That would require virtually no cost and extreme benefit with the molecular cause fabricated from vain imagination and suspended by pure faith.
All responses are welcome, fallacious arguments will be identified and recorded as neutral. All substantive arguments will be addressed, in as much as I'm able, and I have a plan to ensure nothing gets buried in this thread.
Grace and peace,
Mark
Idols of the Theater are those which are due to sophistry and false learning. These idols are built up in the field of theology, philosophy, and science, and because they are defended by learned groups are accepted without question by the masses. When false philosophies have been cultivated and have attained a wide sphere of dominion in the world of the intellect they are no longer questioned. False superstructures are raised on false foundations, and in the end systems barren of merit parade their grandeur on the stage of the world. (Novum Organum)
This grand theatrical production has been performing for over a century now, it's history littered with fabrication. Perhaps the longest running demonstration was easily the Piltdown fraud. The Piltdown Hoax was the flagship transitional of Darwinism for nearly half a century and it was a hoax. A skull taken from a mass gravesite used during the Black Plague matched up with an orangatan jawbone. Even Louise Leakey, the famous paleontologist has said that jaw didn’t belong with that skull so people knew, long before it was exposed, that Piltdown was contrived.
The problem was that there was nothing to replace it as a transitional from ape to man. Concurrent with the prominence of the Piltdown fossil Raymond Dart had reported on the skull of an ape that had filled with lime creating an endocast or a model of what the brain would have looked like. Everyone considered it a chimpanzee child since it’s cranial capacity was just over 400cc but with the demise of Piltdown, a new icon was needed in the Darwinian theater of the mind. Raymond Dart suggests to Louis Leakey that a small brained human ancestor might have been responsible for some of the supposed tools the Leaky family was finding in Africa. The myth of the stone age ape man was born.
The Scottish anthropologist Sir Arthur Keith had built his long and distinguished career on the Piltdown fossil. When it was exposed it sent Darwinians scrambling, Arthur Keith had always rejected the Taung Child (Raymond Dart’s discovery) a chimpanzee child. Rightfully so since it’s small even for a modern chimpanzee. Keith would eventually apologized to Dart and Leakey would take his suggested name for the stone age ape man, Homo habilis, but there was a very real problem. The skull was too small to be considered a human ancestor, this impasse became known as the Cerebral Rubicon and Leakey’s solution was to simply ignore the cranial capacity.
Ever notice that there are no Chimpanzee ancestors in the fossil record? That’s because every time a gracial (smooth) skull, that is dug up in Asian or Africa they are automatically one of our ancestors.
Australopithecus afarensis: AL 288-1
Australopithecus africanus: Taung 1
Lucy a Chimpanzee
Taung Skull not Humn-like 26 August 2014
Australopithecus africanus: Taung 1
Lucy a Chimpanzee
Taung Skull not Humn-like 26 August 2014
These two are the only Hominid fossils I've seen that are really being passed of as transitional. They both have chimpanzee size brains, with all the features one would expect of a knuckle dragging, tree dwelling ape. What is far more important then finding something indicating a transitional fossil, which they have failed to do, is to understand what the basis of the three-fold of the human brain from that of apes:
The evolutionary time separating human and macaque (20–25 million years) is grossly comparable to that separating rat and mouse (16–23 million years)…214 such genes in all of the four taxa chosen…
Increases in brain size and complexity are evident in the evolution of many primate lineages…However, this increase is far more dramatic in the lineage leading to humans than in other primate lineages…
accelerated protein evolution in a large cohort of nervous system genes, which is particularly pronounced for genes involved in nervous system development, represents a salient genetic correlate to the profound changes in brain size and complexity during primate evolution, (Molecular Evolution of the Human Nervous System. Bruce T. Lahn et al. Cell 2004)
Increases in brain size and complexity are evident in the evolution of many primate lineages…However, this increase is far more dramatic in the lineage leading to humans than in other primate lineages…
accelerated protein evolution in a large cohort of nervous system genes, which is particularly pronounced for genes involved in nervous system development, represents a salient genetic correlate to the profound changes in brain size and complexity during primate evolution, (Molecular Evolution of the Human Nervous System. Bruce T. Lahn et al. Cell 2004)
That was probably the broadest comparison of brain related genes between apes and humans shortly after the unveiling of the findings of the Human Genome Project in 2001. Since then they have discovered at least two dramatic giant leaps that would have had to occur in order of the human brain to have emerged from ape like ancestors SRGAP2, HAR1F. In addition genes involved with the development of language (FOXP2), changes in the musculature of the jaw (MYH16) , and limb and digit specializations (HACNS1).
The ancestral SRGAP2 protein sequence is highly constrained based on our analysis of 10 mammalian lineages. We find only a single amino-acid change between human and mouse and no changes among nonhuman primates within the first nine exons of the SRGAP2 orthologs. This is in stark contrast to the duplicate copies, which diverged from ancestral SRGAP2A less than 4 mya, but have accumulated as many as seven amino-acid replacements compared to one synonymous change. (Human-specific evolution of novel SRGAP2 genes by incomplete segmental duplication Cell May 2012)
What is the problem with 7 amino acid replacements in a highly conserved brain related gene? The only observed effects of changes in this gene in humans is disease and disorder:
- 15,767 individuals reported by Cooper et al. (2011)] for potential copy-number variation. We identified six large (>1 Mbp) copy-number variants (CNVs), including three deletions of the ancestral 1q32.1 region…
- A ten year old child with a history of seizures, attention deficit disorder, and learning disabilities. An MRI of this patient also indicates several brain malformations, including hypoplasia of the posterior body of the corpus callosum…
- Translocation breaking within intron 6 of SRGAP2A was reported in a five-year-old girl diagnosed with West syndrome and exhibiting epileptic seizures, intellectual disability, cortical atrophy, and a thin corpus callosum. (Human-specific evolution of novel SRGAP2 genes by incomplete segmental duplication Cell May 2012)
Of course Creationists have their opinions about this gene:
SRGAP2A, SRGAP2B, SRGAP2C, and SRGAP2D, which are located in three completely separate regions on chromosome number 1.1 They appear to play an important role in brain development.2 Perhaps the most striking discovery is that three of the four genes (SRGAP2B, SRGAP2C, and SRGAP2D) are completely unique to humans and found in no other mammal species, not even apes…Unique in their protein coding arrangement and structure. The genes do not look duplicated at all… (Newly Discovered Human Brain Genes Are Bad News for Evolution by Jeffrey P. Tomkins, Ph.D)
In one of the areas of the human genome that would have had to change the most, Human Accelerated Region (HAR), we find a gene that has changed the least over just under 400 million years HAR1F. Just after the Cambrian is would have had to emerge de novo, fully formed, fully functional and permanently fixed along broad taxonomic categories. In all the time since it would allow only two substitutions, then, while the DNA around it is being completely overhauled it allows 18 substitutions in a regulatory gene only 118 nucleotides long. The vital function of this gene cannot be overstated:
The most dramatic of these ‘human accelerated regions’, HAR1, is part of a novel RNA gene (HAR1F) that is expressed specifically in Cajal– Retzius neurons in the developing human neocortex from 7 to 19 gestational weeks, a crucial period for cortical neuron specification and migration. HAR1F is co-expressed with reelin, a product of Cajal–Retzius neurons that is of fundamental importance in specifying the six-layer structure of the human cortex. (An RNA gene expressed during cortical development evolved rapidly in humans, Nature 16 August 2006)
This all has to occur after the chimpanzee human split, while our ancestors were contemporaries in equatorial Africa, with none of the selective pressures effecting our ancestral cousins. This is in addition to no less then 60 de novo (brand new) brain related genes with no known molecular mechanism to produce them. Selection can explain the survival of the fittest but the arrival of the fittest requires a cause:
The de novo origin of a new protein-coding gene from non-coding DNA is considered to be a very rare occurrence in genomes. Here we identify 60 new protein-coding genes that originated de novo on the human lineage since divergence from the chimpanzee. The functionality of these genes is supported by both transcriptional and proteomic evidence. RNA– seq data indicate that these genes have their highest expression levels in the cerebral cortex and testes, which might suggest that these genes contribute to phenotypic traits that are unique to humans, such as improved cognitive ability. Our results are inconsistent with the traditional view that the de novo origin of new genes is very rare, thus there should be greater appreciation of the importance of the de novo origination of genes…(De Novo Origin of Human Protein-Coding Genes Plod 2011)
Whatever you think happened one thing is for sure, random mutations are the worst explanation possible. They cannot produce de novo genes and invariably disrupt functional genes. You can forget about gradual accumulation of, 'slow and gradual accumulation of numerous, slight, yet profitable, variations' (Darwin). That would require virtually no cost and extreme benefit with the molecular cause fabricated from vain imagination and suspended by pure faith.
All responses are welcome, fallacious arguments will be identified and recorded as neutral. All substantive arguments will be addressed, in as much as I'm able, and I have a plan to ensure nothing gets buried in this thread.
Grace and peace,
Mark
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